KPV

What it is:

KPV (Lysine-Proline-Valine) is a naturally occurring tripeptide consisting of three amino acids — lysine, proline, and valine — derived from the C-terminal region of alpha-melanocyte-stimulating hormone (α-MSH). With a molecular formula of C16H30N4O4 and a molecular weight of 342.4 g/mol, it represents the biologically active fragment of α-MSH responsible for its immunomodulatory signaling properties. Its minimal three-amino-acid structure confers notable stability against enzymatic degradation compared to its parent hormone while retaining its core receptor interaction profile. It is used as a research tool in melanocortin receptor biology, inflammatory signaling pathway studies, and gastrointestinal mucosal research.